Article
Mapping of a susceptibility gene for multiple sclerosis to the 51 kb interval between G511525 and D6S1666 using a new method of haplotype sharing analysis.
Neurogenetics - 1 Oct 2001
Boon M, Nolte I M, Bruinenberg M, Spijker G T, Terpstra P, Raelson J, De Keyser J, Zwanikken C P, Hulsbeek M, Hofstra R M, Buys C H, te Meerman G J
Abstract excerpt
Multiple sclerosis (MS) is a complex disease that is partly genetic in origin. Although an association of MS with specific human leukocyte antigen (HLA) types has been known for almost 30 years, the nature of this relationship has remained unclear. Furthermore, genetic resolution sufficient to implicate a specific gene in the HLA region has not been achieved. Many loci in the HLA region have been found to be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.