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Article

Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis.

European journal of human genetics : EJHG - 1 May 2010

Alcina Antonio, Ramagopalan Sreeram V, Fernández Oscar, Catalá-Rabasa Antonio, Fedetz María, Ndagire Dorothy, Leyva Laura, Arnal Carmen, Delgado Concepción, Lucas Miguel, Izquierdo Guillermo, Ebers George C, Matesanz Fuencisla

Abstract excerpt

A recent genome-wide association study (GWAS) performed by the The Wellcome Trust Case-Control Consortium based on 12 374 nonsynonymous single-nucleotide polymorphisms (SNPs) provided evidence for several genes involved in multiple sclerosis (MS) susceptibility. In this study, we aimed at verifying the association of 19 SNPs with MS, with P-values < or =0.005, in an independent cohort of 732 patients and 974...

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Identifiers

PMID: 19935835
DOI: 10.1038/ejhg.2009.213
PMCID: PMC2987318

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