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Article

Gastrointestinal stromal tumor: advances in diagnosis and management.

Archives of pathology & laboratory medicine - 1 Oct 2011

Patil Deepa T, Rubin Brian P

Abstract excerpt

CONTEXT: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract and should be differentiated from other mesenchymal tumors. They harbor specific activating mutations in the KIT or platelet-derived growth factor receptor α ( PDGFRA ) receptor tyrosine kinases, which makes them responsive to pharmacologic inhibitors, such as imatinib mesylate and sunitinib...

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Identifiers

PMID: 21970485
DOI: 10.5858/arpa.2011-0022-RA

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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