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Article

Phosphate-induced vascular calcification: role of pyrophosphate and osteopontin.

Journal of the American Society of Nephrology : JASN - 1 Jun 2004

Lomashvili Koba A, Cobbs Scott, Hennigar Randolph A, Hardcastle Kenneth I, O'Neill W Charles

Abstract excerpt

Hyperphosphatemia is thought to underlie medial vascular calcification in advanced renal failure, but calcification can occur in other conditions in the absence of hyperphosphatemia, indicating that additional factors are important. To identify these factors, a model of medial calcification in rat aorta in vitro was developed. Aortic rings from rats were incubated in serum-free medium for 9 d, and calcification...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15153550
DOI: 10.1097/01.asn.0000128955.83129.9c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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