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Article

Growth-associated hyperphosphatemia in young recipients accelerates aortic allograft calcification in a rat model.

The Journal of thoracic and cardiovascular surgery - 1 Feb 2013

Yamauchi Haruo, Motomura Noboru, Chung Ung-Il, Sata Masataka, Takai Daiya, Saito Aya, Ono Minoru, Takamoto Shinichi

Abstract excerpt

OBJECTIVES: Cardiovascular allografts in the young have limited durability because of early graft calcification. The objective of this study was to examine the hypothesis that growth-associated hyperphosphatemia in youth accelerates aortic allograft calcification by osteogenic transformation of graft medial smooth muscle cells (SMCs). METHODS: The descending aortas of donor rats were subcutaneously transplanted...

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Source

Identifiers

PMID: 22513315
DOI: 10.1016/j.jtcvs.2012.03.010

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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