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Article

Direct effects of phosphate on vascular cell function.

Advances in chronic kidney disease - 1 Mar 2011

Lau Wei Ling, Pai Ashwini, Moe Sharon M, Giachelli Cecilia M

Abstract excerpt

Elevated serum phosphate has clinically been associated with vascular stiffness and cardiovascular mortality. Mechanistic studies over the past decade regarding local effects of phosphate on the vessel wall have provided insight into various pathways that culminate in vascular calcification. Smooth muscle cell phenotype change and apoptosis play prominent roles. The sodium-phosphate cotransporter PiT-1 is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Muscle, Smooth, Vascular

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Share to Sodium-Phosphate Cotransporter Proteins, Type III

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Identifiers

PMID: 21406295
DOI: 10.1053/j.ackd.2010.12.002
PMCID: PMC3086393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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