Article
Pyrophosphate deficiency in vascular calcification.
Kidney international - 1 Jun 2018
Villa-Bellosta Ricardo, O'Neill W Charles
Abstract excerpt
Pathologic cardiovascular calcification is associated with a number of conditions and is a common complication of chronic kidney disease. Because ambient calcium and phosphate levels together with properties of the vascular matrix favor calcification even under normal conditions, endogenous inhibitors such as pyrophosphate play a key role in prevention. Genetic diseases and animal models have elucidated the...
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