Placental-specific insulin-like growth factor 2 ( <i>Igf2</i> ) regulates the diffusional exchange characteristics of the mouse placenta

Abstract excerpt

Restricted fetal growth is associated with postnatal mortality and morbidity and may be directly related to alterations in the capacity of the placenta to supply nutrients. We proposed previously that imprinted genes can regulate nutrient supply by the placenta. Here, we tested the hypothesis that the insulin-like growth factor 2 gene (Igf2) transcribed from the placental-specific promoter (P0) regulates the...

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