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Article

Placental-specific <i>Igf2</i> knockout mice exhibit hypocalcemia and adaptive changes in placental calcium transport

4 Feb 2010

Abstract excerpt

Evidence is emerging that the ability of the placenta to supply nutrients to the developing fetus adapts according to fetal demand. To examine this adaptation further, we tested the hypothesis that placental maternofetal transport of calcium adapts according to fetal calcium requirements. We used a mouse model of fetal growth restriction, the placental-specific Igf2 knockout (P0) mouse, shown previously to...

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PMID: 20133672
DOI: 10.1073/pnas.0911710107

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