Article
Adaptations in placental phenotype support fetal growth during undernutrition of pregnant mice.
The Journal of physiology - 1 Feb 2010
Coan P M, Vaughan O R, Sekita Y, Finn S L, Burton G J, Constancia M, Fowden A L
Abstract excerpt
Undernutrition during pregnancy reduces birth weight and programmes adult phenotype with consequences for life expectancy, but its effects on the phenotype of the placenta, responsible for supplying nutrients for fetal growth, remain largely unknown. Using molecular, morphological and functional analyses, placental phenotype was examined in mice during restriction of dietary intake to 80% of control from day 3 of...
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