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Article

Engagement of protein kinase C-theta in interferon signaling in T-cells.

The Journal of biological chemistry - 16 Jul 2004

Srivastava Kishore K, Batra Sandeep, Sassano Antonella, Li Yongzhong, Majchrzak Beata, Kiyokawa Hiroaki, Altman Amnon, Fish Eleanor N, Platanias Leonidas C

Abstract excerpt

Protein kinase C-theta (PKC-theta) plays important roles in the activation and survival of lymphocytes and is the predominant PKC isoform expressed in T-cells. Interferons regulate T-cell function and activation, but the precise signaling mechanisms by which they mediate such effects have not been elucidated. We determined whether PKC-theta is engaged in interferon (INF) signaling in T-cells. Both Type I (alpha,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15150272
DOI: 10.1074/jbc.M401997200

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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