Article
Protein kinase C theta (PKCtheta): a key player in T cell life and death.
Pharmacological research - 1 Jun 2007
Hayashi Keitaro, Altman Amnon
Abstract excerpt
Protein kinase C theta (PKCtheta) is a member of the novel, Ca(2+)-independent PKC subfamily, which plays an important and non-redundant role in several aspects of T cell biology. Much progress has been accomplished in understanding the function of PKCtheta in the immune system and its unique translocation to the immunological synapse in Ag-stimulated T lymphocytes. Biochemical and genetic approaches revealed...
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