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Article

Estrogen receptor alpha-mediated events promote sex-specific diabetic glomerular hypertrophy.

American journal of physiology. Renal physiology - 1 Sept 2004

Lovegrove Alecia S, Sun Jianhong, Gould Karen A, Lubahn Dennis B, Korach Kenneth S, Lane Pascale H

Abstract excerpt

Sex differences in the incidence and progression of renal diseases suggest a protective role for estrogen. This study examined the role of estrogen receptor alpha (ERalpha)-mediated events in normal and diabetic renal and glomerular growth. Wild-type and ERalpha-null mice (ERKO) were observed over 2 wk of streptozocin-induced diabetes. Blood glucose was monitored, and insulin was given daily to maintain levels of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15149972
DOI: 10.1152/ajprenal.00414.2003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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