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Article

Sexual dimorphism in the glucose homeostasis phenotype of the Aromatase Knockout (ArKO) mice.

The Journal of steroid biochemistry and molecular biology - 1 Jun 2017

Van Sinderen Michelle, Steinberg Gregory, Jorgensen Sebastian B, Honeyman Jane, Chow Jenny D Y, Simpson Evan R, Jones Margaret E E, Boon Wah Chin

Abstract excerpt

We investigated the effects of estrogens on glucose homeostasis using the Aromatase Knockout (ArKO) mouse, which is unable to convert androgens into estrogens. The ArKO mouse is a model of total estrogen ablation which develops symptoms of metabolic syndrome. To determine the development and progression of whole body state of insulin resistance of ArKO mice, comprehensive whole body tolerance tests were performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27353462
DOI: 10.1016/j.jsbmb.2016.05.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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