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Article

The Role of the EGF Receptor in Sex Differences in Kidney Injury.

Journal of the American Society of Nephrology : JASN - 1 Sept 2019

Zhang Ming-Zhi, Sasaki Kensuke, Li Yan, Li Zhilian, Pan Yu, Jin Guan-Nan, Wang Yinqiu, Niu Aolei, Wang Suwan, Fan Xiaofeng, Chen Jian Chun, Borza Corina, Yang Haichun, Pozzi Ambra, Fogo Agnes B, Harris Raymond C

Abstract excerpt

BACKGROUND: Sex differences mediating predisposition to kidney injury are well known, with evidence indicating lower CKD incidence rates and slower decline in renal function in nondiabetic CKD for premenopausal women compared with men. However, signaling pathways involved have not been elucidated to date. The EGF receptor (EGFR) is widely expressed in the kidney in glomeruli and tubules, and persistent and...

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Source

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Identifiers

PMID: 31292196
DOI: 10.1681/ASN.2018121244
PMCID: PMC6727256

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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