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Article

Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1.

BMC cell biology - 16 May 2004

Nourry Claire, Maksumova Lola, Pang Mona, Liu Xiaohong, Wang Tongwen

Abstract excerpt

BACKGROUND: The Transforming Growth Factor-beta (TGF-beta) regulates myriad cellular events by signaling through members of the Smad family signal transducers. As a key signal transducer of TGF-beta, Smad3 exhibits the property of receptor-activated transcriptional modulator and also the novel ability of regulating the proteasomal degradation of two Smad3 interacting proteins, SnoN and HEF1. It has been shown...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 15144564
DOI: 10.1186/1471-2121-5-20
PMCID: PMC420458

Genes

APC
CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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