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Article

Current perspectives on inhibitory SMAD7 in health and disease

20 Oct 2020

Abstract excerpt

Transforming growth factor β (TGF-β) family members play an extensive role in cellular communication that orchestrates both early development and adult tissue homeostasis. Aberrant TGF-β family signaling is associated with a pathological outcome in numerous diseases, and in-depth understanding of molecular and cellular processes could result in therapeutic benefit for patients. Canonical TGF-β signaling is...

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PMID: 33081543
DOI: 10.1080/10409238.2020.1828260

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