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Article

Regulation of constitutive p50/c-Rel activity via proteasome inhibitor-resistant IkappaBalpha degradation in B cells.

Molecular and cellular biology - 1 Jun 2004

O'Connor Shelby, Shumway Stuart D, Amanna Ian J, Hayes Colleen E, Miyamoto Shigeki

Abstract excerpt

Constitutive NF-kappaB activity has emerged as an important cell survival component of physiological and pathological processes, including B-cell development. In B cells, constitutive NF-kappaB activity includes p50/c-Rel and p52/RelB heterodimers, both of which are critical for proper B-cell development. We previously reported that WEHI-231 B cells maintain constitutive p50/c-Rel activity via selective...

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PMID: 15143182
DOI: 10.1128/MCB.24.11.4895-4908.2004
PMCID: PMC416427

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PIR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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