Article
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100.
Molecular cell - 1 Feb 2001
Xiao G, Harhaj E W, Sun S C
Abstract excerpt
Processing of the nf(kappa)b2 gene product p100 to generate p52 is an important step in NF-kappaB regulation. We show that this step is negatively regulated by a processing-inhibitory domain (PID) within p100 and positively regulated by the NF-kappaB-inducing kinase (NIK). While the PID suppresse...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
