Article
Atherosclerotic plaque smooth muscle cells have a distinct phenotype.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2004
Mulvihill Eileen R, Jaeger Jochen, Sengupta Rimli, Ruzzo Walter L, Reimer Cecile, Lukito Sheila, Schwartz Stephen M
Abstract excerpt
OBJECTIVE: The present study addresses the question, "Are plaque smooth muscles cells (SMCs) genetically distinct from medial SMCs as reflected by the ability to maintain a distinctive expression phenotype in vitro?" METHODS AND RESULTS: Multiple cell strains were developed from carotid endarcterectomy specimens, and quadruplicate array hybridizations were completed for each sample. A new normalization protocol...
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