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Article

Coordinate downregulation of a novel imprinted transcript ITUP1 with PEG3 in glioma cell lines.

DNA research : an international journal for rapid publication of reports on genes and genomes - 29 Feb 2004

Maegawa Shinji, Itaba Noriko, Otsuka Susumu, Kamitani Hideki, Watanabe Takashi, Tahimic Candice G T, Nanba Eiji, Oshimura Mitsuo

Abstract excerpt

The human paternally expressed gene 3 (PEG3) on chromosome 19q13.4 is one of the candidate tumor suppressor genes for glioma. We have previously reported that the epigenetic silencing of PEG3 expression in glioma cell lines is dependent on aberrant DNA methylation of an exonic CpG island. Here, we have identified three expressed sequence tags (ESTs), H80201, H78825 and AW197312, that exhibit paternal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15141944
DOI: 10.1093/dnares/11.1.37

Genes

PEG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Coordinate downregulation of a novel imprinted transcript ITUP1 with PEG3 in glioma cell lines.PMID 15141944Read ↗

Epigenetic silencing of <i>PEG3</i> gene expression in human glioma cell lines*Semantic proximity Read ↗

Tumour suppressor activity of human imprinted gene <i>PEG3</i> in a glioma cell lineSemantic proximity Read ↗

An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa.Semantic proximity Read ↗

Downregulation of long non‐coding RNA MEG3 in nasopharyngeal carcinomaSemantic proximity Read ↗

DNA hypermethylation and aberrant expression of the EMP3 gene at 19q13.3 in Human Gliomas.Semantic proximity Read ↗

Identification of an Evolutionarily Conserved Cis-Regulatory Element Controlling the Peg3 Imprinted DomainSemantic proximity Read ↗

Involvement of parental imprinting in the antisense regulation of onco-miR-372-373.Semantic proximity Read ↗

A Pituitary-Derived MEG3 Isoform Functions as a Growth Suppressor in Tumor CellsSemantic proximity Read ↗

Allele-specific enhancer interaction at the Peg3 imprinted domain.Semantic proximity Read ↗

<i>EMP3</i>, a Myelin-Related Gene Located in the Critical 19q13.3 Region, Is Epigenetically Silenced and Exhibits Features of a Candidate Tumor Suppressor in Glioma and NeuroblastomaSemantic proximity Read ↗

Monoallelic expression of human PEG1/MEST is paralleled by parent-specific methylation in fetuses.Semantic proximity Read ↗

Allele-specific methylation of a functional CTCF binding site upstream of MEG3 in the human imprinted domain of 14q32.Semantic proximity Read ↗

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