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Article

Monoallelic expression of human PEG1/MEST is paralleled by parent-specific methylation in fetuses.

Genomics - 1 Jun 1997

Riesewijk A M, Hu L, Schulz U, Tariverdian G, Höglund P, Kere J, Ropers H H, Kalscheuer V M

Abstract excerpt

We have isolated the human PEG1/MEST gene and have investigated its imprinting status and parental-specific methylation. FISH mapping assigned the gene to chromosome 7q32, and homologous sequences were identified on the short arm of human chromosomes 3 and 5. Through the use of a newly identified intragenic polymorphism, expression analysis revealed that PEG1/MEST is monoallelically transcribed in all fetal...

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Source

Identifiers

PMID: 9192843
DOI: 10.1006/geno.1997.4731

Genes

MEST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Monoallelic expression of human PEG1/MEST is paralleled by parent-specific methylation in fetuses.PMID 9192843Read ↗

Genomic Structure and Parent-of-Origin-Specific Methylation of Peg1Semantic proximity Read ↗

Imprinting of PEG1/MEST isoform 2 in human placenta.Semantic proximity Read ↗

An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa.Semantic proximity Read ↗

Identification and characterization of an imprinted antisense RNA (MESTIT1) in the human MEST locus on chromosome 7q32Semantic proximity Read ↗

Isoform-Specific Imprinting of the Human PEG1/MEST GeneSemantic proximity Read ↗

Hypermethylation of the non-imprinted maternal MEG3 and paternal MEST alleles is highly variable among normal individuals.Semantic proximity Read ↗

Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing.Semantic proximity Read ↗

Imprinting analysis of 10 genes and/or transcripts in a 1.5-Mb MEST-flanking region at human chromosome 7q32.Semantic proximity Read ↗

Paternal monoallelic expression of PEG3 in the human placentaSemantic proximity Read ↗

The PcG gene Sfmbt2 is paternally expressed in extraembryonic tissues.Semantic proximity Read ↗

Allele-specific Methylation of Imprinted Genes in Fetal Cord Blood is Influenced By Cis-Acting Genetic Variants and Parental FactorsSemantic proximity Read ↗

Peg1/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridizationSemantic proximity Read ↗

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