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Article

An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa.

The Journal of biological chemistry - 19 Apr 2002

Li Tao, Vu Thanh H, Lee Kok-Onn, Yang Youwen, Nguyen Chuyen V, Bui Huy Q, Zeng Zhi-Lan, Nguyen Binh T, Hu Ji-Fan, Murphy Susan K, Jirtle Randy L, Hoffman Andrew R

Abstract excerpt

PEG1 (or MEST) is an imprinted gene located on human chromosome 7q32 that is expressed predominantly from the paternal allele. In the mouse, Peg1/Mest is associated with embryonic growth and maternal behavior. Human PEG1 is transcribed from two promoters; the transcript from promoter P1 is derived from both parental alleles, and the transcript from P2 is exclusively from the paternal allele. We characterized the...

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Source

Identifiers

PMID: 11821432
DOI: 10.1074/jbc.M200458200

Genes

MEST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa.PMID 11821432Read ↗

Monoallelic expression of human PEG1/MEST is paralleled by parent-specific methylation in fetuses.Semantic proximity Read ↗

Imprinting of PEG1/MEST isoform 2 in human placenta.Semantic proximity Read ↗

Genomic Structure and Parent-of-Origin-Specific Methylation of Peg1Semantic proximity Read ↗

Isoform-Specific Imprinting of the Human PEG1/MEST GeneSemantic proximity Read ↗

Identification and characterization of an imprinted antisense RNA (MESTIT1) in the human MEST locus on chromosome 7q32Semantic proximity Read ↗

Multiple Imprinted and Stemness Genes Provide a Link between Normal and Tumor Progenitor Cells of the Developing Human KidneySemantic proximity Read ↗

<i>PEG10</i> Is a c-MYC Target Gene in Cancer CellsSemantic proximity Read ↗

Mouse <i>Peg9/Dlk1</i> and human <i>PEG9/DLK1</i> are paternally expressed imprinted genes closely located to the maternally expressed imprinted genes: mouse <i>Meg3/Gtl2</i> and human <i>MEG3</i>Semantic proximity Read ↗

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