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Article

Tumour suppressor activity of human imprinted gene <i>PEG3</i> in a glioma cell line

1 Mar 2001

Abstract excerpt

BACKGROUND: Mouse imprinted gene Peg3 encodes a large C2H2 type zinc finger protein with unique characteristics. Peg3 knockout mice were found to show an impairment in maternal behaviour of the adult female. Mouse Peg3 is located on the proximal region of chromosome 7 which is syntenic to the long arm of human chromosome 19. It has been reported that a loss of heterozygosity (LOH) of chromosome 19q occurs...

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PMID: 11260267
DOI: 10.1046/j.1365-2443.2001.00412.x

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