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Article

Interleukin-18-promoter polymorphisms are not relevant in rheumatoid arthritis.

Tissue antigens - 1 Jun 2005

Rueda B, González-Gay M A, Mataran L, López-Nevot M A, Martín J

Abstract excerpt

Interleukin-18 (IL-18), a member of the IL-1 family, is known to play a relevant role in rheumatoid arthritis (RA) physiopathology mainly by promoting the inflammatory response. The aim of this work was to investigate the possible implication of two single-nucleotide polymorphisms (SNPs) [-607 A/C (rs1946518) and -137 G/C (rs187238)] within the IL-18-promoter region in RA predisposition and clinical course. A...

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Identifiers

PMID: 15896202
DOI: 10.1111/j.1399-0039.2005.00408.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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