Article
Promoter polymorphism of IL-18 gene in pulmonary tuberculosis in South Indian population.
International journal of immunogenetics - 1 Oct 2007
Harishankar M, Selvaraj P, Rajeswari D N, Anand S P, Narayanan P R
Abstract excerpt
Interleukin-18 (IL-18) plays a vital role in both innate and acquired immunity. We analysed polymorphisms at -607(C/A) and -137(G/A) in the promoter region of IL-18 gene by allele-specific polymerase chain reaction in normal healthy subjects (n = 173) and patients with pulmonary tuberculosis (n = 165). Allele, genotype and haplotype frequencies did not differ significantly between normal healthy subjects and...
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