Article
Age influences resistance of Caenorhabditis elegans to killing by pathogenic bacteria.
FEMS microbiology letters - 15 May 2004
Laws Thomas R, Harding Sarah V, Smith Martin P, Atkins Timothy P, Titball Richard W
Abstract excerpt
Caenorhabditis elegans has previously been proposed as an alternative host for models of infectious disease caused by human pathogens. When exposed to some human pathogenic bacteria, the life span of nematodes is significantly reduced. We have shown that mutations in the age-1, and/or age-2 genes of C. elegans, that normally enhance life expectancy, can also increase resistance to killing by the bacterial...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.