Article
Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans.
BMC microbiology - 27 Mar 2012
Portal-Celhay Cynthia, Bradley Ellen R, Blaser Martin J
Abstract excerpt
BACKGROUND: A powerful approach to understanding complex processes such as aging is to use model organisms amenable to genetic manipulation, and to seek relevant phenotypes to measure. Caenorhabditis elegans is particularly suited to studies of aging, since numerous single-gene mutations have been identified that affect its lifespan; it possesses an innate immune system employing evolutionarily conserved...
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