Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans.

BMC microbiology - 27 Mar 2012

Portal-Celhay Cynthia, Bradley Ellen R, Blaser Martin J

Abstract excerpt

BACKGROUND: A powerful approach to understanding complex processes such as aging is to use model organisms amenable to genetic manipulation, and to seek relevant phenotypes to measure. Caenorhabditis elegans is particularly suited to studies of aging, since numerous single-gene mutations have been identified that affect its lifespan; it possesses an innate immune system employing evolutionarily conserved...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteria
Share to Bacterial Load
Share to Caenorhabditis elegans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Caenorhabditis elegans Proteins

Share to Intestines

Share to Longevity

Share to Receptor, Insulin

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 22452899
DOI: 10.1186/1471-2180-12-49
PMCID: PMC3342110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans.PMID 22452899Read ↗

A diet of oxidative stress-adapted bacteria improves stress resistance and lifespan in <i>C. elegans</i> via p38-MAPKSemantic proximity Read ↗

Microbes are potential key players in the evolution of life histories and aging in <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

Iron-deplete diet enhances Caenorhabditis elegans lifespan via oxidative stress response pathways.Semantic proximity Read ↗

Commensals, probiotics and pathogens in the C aenorhabditis elegans modelSemantic proximity Read ↗

Evolution of lifespan in C. elegans.Semantic proximity Read ↗

Genetics of lifespan in C. elegans: molecular diversity, physiological complexity, mechanistic simplicity.Semantic proximity Read ↗

Caenorhabditis elegans: What We Can and Cannot Learn from Aging Worms.Semantic proximity Read ↗

The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity.Semantic proximity Read ↗

The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans.Semantic proximity Read ↗

Bacterial RNA promotes proteostasis through inter-tissue communication in <i>C. elegans</i>Semantic proximity Read ↗

Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegansSemantic proximity Read ↗

Using Caenorhabditis elegans as a model for aging and age-related diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.