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Caenorhabditis elegans Aurora A kinase AIR-1 is required for postembryonic cell divisions and germline development.

Genesis (New York, N.Y. : 2000) - 1 Dec 2002

Furuta Tokiko, Baillie David L, Schumacher Jill M

Abstract excerpt

Many kinases are required for progression through the eukaryotic cell cycle. The Aurora kinases comprise a highly conserved family of serine/threonine kinases that have been implicated in chromosome segregation and cytokinesis in several organisms. We have isolated a sterile Caenorhabditis elegan...

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PMID: 12434334
DOI: 10.1002/gene.10157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12434334-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Caenorhabditis elegans Aurora A kinase AIR-1 is required for postembryonic cell divisions and germline development.PMID 12434334Read ↗

A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in <i>Caenorhabditis elegans</i> embryosSemantic proximity Read ↗

Stu-7/air-2 is a C. elegans aurora homologue essential for chromosome segregation during embryonic and post-embryonic development.Semantic proximity Read ↗

An Afg2/Spaf-related Cdc48-like AAA ATPase regulates the stability and activity of the C. elegans Aurora B kinase AIR-2.Semantic proximity Read ↗

Characterization of Ce-atl-1, an ATM-like gene from Caenorhabditis elegans.Semantic proximity Read ↗

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An RNAi screen for conserved kinases that enhance microRNA activity after dauer in Caenorhabditis elegans.Semantic proximity Read ↗

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles.Semantic proximity Read ↗

EYA-1 is required for genomic integrity independent of H2AX signalling in Caenorhabditis elegans.Semantic proximity Read ↗

C. elegans RBX-2-CUL-5- and RBX-1-CUL-2-based complexes are redundant for oogenesis and activation of the MAP kinase MPK-1.Semantic proximity Read ↗

The aurora kinase AIR-2 functions in the release of chromosome cohesion in Caenorhabditis elegans meiosis.Semantic proximity Read ↗

emb-1 encodes the APC16 subunit of the Caenorhabditis elegans anaphase-promoting complex.Semantic proximity Read ↗

Evolutionary relationships of Aurora kinases: Implications for model organism studies and the development of anti-cancer drugsSemantic proximity Read ↗

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