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Article

Family based association analysis of the IL2 and IL15 genes in allergic disorders.

European journal of human genetics : EJHG - 1 Feb 2006

Christensen Ulla, Haagerup Annette, Binderup Helle G, Vestbo Jørgen, Kruse Torben A, Børglum Anders D

Abstract excerpt

Allergic diseases affect an increasing number of individuals and are a major global health problem. A substantial genetic contribution in the aetiology of allergic diseases is well documented. We have previously reported linkage of allergic diseases and atopy to the region harbouring the IL2 gene (4q27). IL15 is located approximately 20 Mb distal to IL2. The two genes encode cytokines that are structurally and...

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PMID: 16333313
DOI: 10.1038/sj.ejhg.5201541

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