Article
IL15 gene variants are not associated with asthma and atopy.
Allergy - 1 Apr 2009
Pinto L A, Depner M, Steudemann L, Klopp N, Illig T, von Mutius E, Kabesch M
Abstract excerpt
BACKGROUND: Interleukin 15 (IL15) promotes activation and proliferation of CD8+ T cells and enhances the differentiation into Th2 cells. A previous study described five polymorphisms in the IL15 gene to be associated with asthma in a haplotype analysis. AIM: We selected HapMap tagging single nucleotide polymorphisms (SNPs) from IL15 to systematically investigate these IL15 associations in a large population-based...
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