Article
A novel approach to understanding the role of polymorphic forms of the NR3C1 and TGF-β1 genes in the modulation of the expression of IL-5 and IL-15 mRNA in asthmatic inflammation.
Molecular medicine reports - 1 Jun 2016
Panek Michał, Jonakowski Mateusz, Zioło Jan, Wieteska Łukasz, Małachowska Beata, Pietras Tadeusz, Szemraj Janusz, Kuna Piotr
Abstract excerpt
The aim of the present study was to identify polymorphic forms of the nuclear receptor subfamily 3, group C, member 1 (NR3C1) and transforming growth factor β1 (TGF-β1) genes and evaluate their impact on the expression levels of interleukin (IL)-5 and IL‑15 in asthma. The study was conducted on a control group consisting of 91 people (54 women and 37 men). The patient group consisted of 130 participants (86 women...
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