Article
A single nucleotide polymorphism (A --> G) in intron 3 of IFNgamma gene is associated with asthma.
Genes and immunity - 1 Jun 2008
Kumar A, Ghosh B
Abstract excerpt
Interferon-gamma (IFNgamma) is located on chromosome 12, and a number of studies have detected very strong linkage signals around this gene and asthma. The aim of this study was to analyze the association of a (CA)n repeat in intron 1 and six single nucleotide polymorphisms (((rs2069705, T/C) (promoter)), ((rs1861494, A/G), (rs1861493, T/C), (rs2069718, C/T) (intron 3)), ((rs2069727, A/G) and (, G/A) (3'...