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Article

Prevalence and characterization of a binary toxin (actin-specific ADP-ribosyltransferase) from Clostridium difficile.

Journal of clinical microbiology - 1 May 2004

Gonçalves Carina, Decré Dominique, Barbut Frédéric, Burghoffer Béatrice, Petit Jean-Claude

Abstract excerpt

In addition to the two large clostridial cytotoxins (TcdA and TcdB), some strains of Clostridium difficile also produce an actin-specific ADP-ribosyltransferase, called binary toxin CDT. We used a PCR method and Southern blotting for the detection of genes encoding the enzymatic (CDTa) and binding (CDTb) components of the binary toxin in 369 strains isolated from patients with suspected C. difficile-associated...

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Source

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Identifiers

PMID: 15131151
DOI: 10.1128/JCM.42.5.1933-1939.2004
PMCID: PMC404597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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