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A Hospital Outbreak of Clostridium difficile Disease Associated with Isolates Carrying Binary Toxin Genes

30 Dec 2004

Abstract excerpt

INTRODUCTION: The binary toxin genes cdt and cdtB have been detected in approximately 5% of Clostridium difficile strains. Severe C. difficile disease (CDD) may be associated with strains that carry the binary toxin genes. METHODS: From April 2001 through March 2002, 8 severe and 41 nonsevere cases of nosocomial CDD were studied. Severe cases of CDD were defined by the presence of >or=2 of the following criteria:...

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PMID: 15655746
DOI: 10.1086/427113

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