Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An Update on Clostridioides difficile Binary Toxin

27 Apr 2022

Abstract excerpt

Infection with Clostridioides difficile (CDI), a common healthcare-associated infection, includes symptoms ranging from mild diarrhea to severe cases of pseudomembranous colitis. Toxin A (TcdA) and toxin B (TcdB) cause cytotoxicity and cellular detachment from intestinal epithelium and are responsible for CDI symptomatology. Approximately 20% of C. difficile strains produce a binary toxin (CDT) encoded by the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clostridium difficile and Clostridium perfringens research
Share to Helicobacter pylori-related gastroenterology studies
Share to Microscopic Colitis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35622552
DOI: 10.3390/toxins14050305

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An Update on Clostridioides difficile Binary ToxinPMID 35622552Read ↗

Genomic and phenotypic studies among Clostridioides difficile isolates show a high prevalence of clade 2 and great diversity in clinical isolates from Mexican adults and children with healthcare-associated diarrhea.Semantic proximity Read ↗

Binary toxin expression by <i>Clostridioides difficile</i> is associated with worse diseaseSemantic proximity Read ↗

Genomic and phenotypic studies among <i>Clostridioides difficile</i> isolates show a high prevalence of clade 2 and great diversity in clinical isolates from Mexican adults and children with healthcare-associated diarrheaSemantic proximity Read ↗

Subtyping analysis reveals new variants and accelerated evolution of Clostridioides difficile toxin B.Semantic proximity Read ↗

<i>Clostridium difficile</i>virulence factors: Insights into an anaerobic spore-forming pathogenSemantic proximity Read ↗

Influence of Binary Toxin Gene Detection and Decreased Susceptibility to Antibiotics among Clostridioides difficile Strains on Disease Severity: a Single-Center StudySemantic proximity Read ↗

Toxin genotypes, antibiotic resistance and their correlations in Clostridioides difficile isolated from hospitals in Xi'an, China.Semantic proximity Read ↗

Characterization of the virulence of a non-RT027, non-RT078 and binary toxin-positive Clostridium difficile strain associated with severe diarrheaSemantic proximity Read ↗

Ribotype Classification of Clostridioides difficile Isolates Is Not Predictive of the Amino Acid Sequence Diversity of the Toxin Virulence Factors TcdA and TcdBSemantic proximity Read ↗

Pathogenicity and virulence of Clostridioides difficileSemantic proximity Read ↗

Clostridium difficile infectionSemantic proximity Read ↗

Clostridioides difficile as a Potential Pathogen of Importance to One Health: A ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.