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Article

Production of a complete binary toxin (actin-specific ADP-ribosyltransferase) by Clostridium difficile CD196

1 Apr 1997

Abstract excerpt

A Clostridium difficile isolate was found to produce an actin-specific ADP-ribosyltransferase (CDT) homologous to the enzymatic components of Clostridium perfringens iota toxin and Clostridium spiroforme toxin (M. R. Popoff, E. J. Rubin, D. M. Gill, and P. Boquet, Infect. Immun. 56:2299-2306, 1988). The CDT locus from C. difficile CD196 was cloned and sequenced. It contained two genes (cdtA and cdtB) which...

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Identifiers

PMID: 9119480
DOI: 10.1128/iai.65.4.1402-1407.1997

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