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Prevalence and pathogenicity of binary toxin–positive Clostridium difficile strains that do not produce toxins A and B

4 Dec 2014

Abstract excerpt

Clostridium difficile causes antibiotic-associated diarrhoea and pseudomembranous colitis. The main virulence factors of C. difficile are the toxins A (TcdA) and B (TcdB). A third toxin, called binary toxin (CDT), can be detected in 17% to 23% of strains, but its role in human disease has not been clearly defined. We report six independent cases of patients with diarrhoea suspected of having C. difficile...

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Identifiers

PMID: 25755885
DOI: 10.1016/j.nmni.2014.10.003

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