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Clostridial Binary Toxins: Iota and C2 Family Portraits

1 Jan 2011

Abstract excerpt

There are many pathogenic Clostridium species with diverse virulence factors that include protein toxins. Some of these bacteria, such as C. botulinum, C. difficile, C. perfringens, and C. spiroforme, cause enteric problems in animals as well as humans. These often fatal diseases can partly be attributed to binary protein toxins that follow a classic AB paradigm. Within a targeted cell, all clostridial binary...

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PMID: 22919577
DOI: 10.3389/fcimb.2011.00011

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