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Article

The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development.

Genes & development - 15 May 2004

Vaucheret Hervé, Vazquez Franck, Crété Patrice, Bartel David P

Abstract excerpt

MicroRNAs (miRNAs) are endogenous 21-24-nt RNAs that can down-regulate gene expression by pairing to the messages of protein-coding genes to specify mRNA cleavage or repression of productive translation. They act within the RNA-induced silencing complex (RISC), which in animals contains a member of the Argonaute family of proteins. In the present study, we show that Arabidopsis ago1 mutants have increased...

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Identifiers

PMID: 15131082
DOI: 10.1101/gad.1201404
PMCID: PMC415643

Genes

AGO1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development.PMID 15131082Read ↗

AGO1 homeostasis entails coexpression of MIR168 and AGO1 and preferential stabilization of miR168 by AGO1.Semantic proximity Read ↗

Controlled RISC loading efficiency of miR168 defined by miRNA duplex structure adjusts ARGONAUTE1 homeostasis.Semantic proximity Read ↗

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mRNA Decay of Most Arabidopsis miRNA Targets Requires Slicer Activity of AGO1.Semantic proximity Read ↗

Transcriptome analyses revealed diverse expression changes in ago1 and hyl1 Arabidopsis mutants.Semantic proximity Read ↗

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Diversity, expression and mRNA targeting abilities of Argonaute-targeting miRNAs among selected vascular plants.Semantic proximity Read ↗

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AGO1 homeostasis involves differential production of 21-nt and 22-nt miR168 species by MIR168a and MIR168b.Semantic proximity Read ↗

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