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Article

AGO1 homeostasis entails coexpression of MIR168 and AGO1 and preferential stabilization of miR168 by AGO1.

Molecular cell - 7 Apr 2006

Vaucheret Hervé, Mallory Allison C, Bartel David P

Abstract excerpt

Arabidopsis ARGONAUTE1 (AGO1) encodes the RNA slicer enzyme of the microRNA (miRNA) pathway and is regulated by miR168-programmed, AGO1-catalyzed mRNA cleavage. Here, we describe two additional regulatory processes required for AGO1 homeostasis: transcriptional coregulation of MIR168 and AGO1 gen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16600876
DOI: 10.1016/j.molcel.2006.03.011
PMCID: PMC2323247

Genes

AGO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16600876-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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AGO1 homeostasis entails coexpression of MIR168 and AGO1 and preferential stabilization of miR168 by AGO1.PMID 16600876Read ↗

The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development.Semantic proximity Read ↗

Controlled RISC loading efficiency of miR168 defined by miRNA duplex structure adjusts ARGONAUTE1 homeostasis.Semantic proximity Read ↗

mRNA Decay of Most Arabidopsis miRNA Targets Requires Slicer Activity of AGO1.Semantic proximity Read ↗

The miRNA pathway limits AGO1 availability during siRNA-mediated PTGS defense against exogenous RNA.Semantic proximity Read ↗

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