Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Non-sequencing molecular approaches to identify preS2-defective hepatitis B virus variants proved to be associated with severe liver diseases.

Journal of hepatology - 1 Mar 2004

Raimondo Giovanni, Costantino Lucy, Caccamo Gaia, Pollicino Teresa, Squadrito Giovanni, Cacciola Irene, Brancatelli Santa

Abstract excerpt

BACKGROUND/AIMS: PreS2-defective hepatitis B virus (HBV) variants may emerge during chronic HBV infection. These variants carry mutation(s) at the ATG-start-codon and/or in-frame deletion into the preS2 genomic region and are commonly detected by sequencing analyses. We evaluated the prevalence of these variants in a large series of chronic HBV infected patients through non-sequencing molecular approaches....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier State
Share to Codon, Initiator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoresis, Agar Gel

Share to Genetic Techniques

Share to Hepatitis B, Chronic

Share to Hepatitis B Surface Antigens

Share to Liver Diseases

Share to Protein Precursors

Source

Identifiers

PMID: 15123368
DOI: 10.1016/j.jhep.2003.11.025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Non-sequencing molecular approaches to identify preS2-defective hepatitis B virus variants proved to be associated with severe liver diseases.PMID 15123368Read ↗

Hepatitis B virus PreS2 mutants in liver cancer patients.Semantic proximity Read ↗

Molecular analysis of Hepatitis B virus sub-genotypes and incidence of preS1/preS2 region mutations in HBV-infected Egyptian patients from Mansoura.Semantic proximity Read ↗

The preS deletion of hepatitis B virus (HBV) is associated with liver fibrosis progression in patients with chronic HBV infection.Semantic proximity Read ↗

Replicating and virion secreting hepatitis B mutant virus unable to produce preS2 protein.Semantic proximity Read ↗

Hepatitis B virus variant, with a deletion in the preS2 and two translational stop codons in the precore regions, in a patient with hepatocellular carcinoma.Semantic proximity Read ↗

Sequence analysis and functional characterization of full-length hepatitis B virus genomes from Korean cirrhotic patients with or without liver cancer.Semantic proximity Read ↗

[Analysis of hepatitis B virus (HBV) preS1, preS2 and S gene regions from patient groups infected with HBV genotype D].Semantic proximity Read ↗

PreS1 deleted variants of hepatitis B virus in patients with chronic hepatitis.Semantic proximity Read ↗

Mutations in the HBV PreS/S gene related to hepatocellular carcinoma in Vietnamese chronic HBV-infected patients.Semantic proximity Read ↗

Significant association of different preS mutations with hepatitis B-related cirrhosis or hepatocellular carcinoma.Semantic proximity Read ↗

Characterization of Novel Hepatitis B Virus PreS/S-Gene Mutations in a Patient with Occult Hepatitis B Virus Infection.Semantic proximity Read ↗

PreS and Core Gene Heterogeneity in Hepatitis B Virus (HBV) Genomes Isolated from Patients with Long-Lasting HBV Chronic InfectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.