Article
Significant association of different preS mutations with hepatitis B-related cirrhosis or hepatocellular carcinoma.
Journal of gastroenterology - 1 Oct 2010
Yin Jianhua, Xie Jiaxin, Zhang Hongwei, Shen Qiuxia, Han Lei, Lu Wenying, Han Yifang, Li Chengzhong, Ni Wu, Wang Hongyang, Cao Guangwen
Abstract excerpt
BACKGROUND: The associations of nucleotide substitution mutations in the preS region of hepatitis B virus (HBV) with hepatocellular carcinoma (HCC) and cirrhosis remain unknown. We aimed to determine the associations of preS mutations with HCC or cirrhosis. METHODS: HBV from 603 asymptomatic hepatitis B surface antigen carriers (ASCs), 219 chronic hepatitis B (CHB) patients, 119 cirrhosis patients, and 231 HCC...
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