Article
Sec8p and Sec15p are components of a plasma membrane-associated 19.5S particle that may function downstream of Sec4p to control exocytosis.
The Journal of cell biology - 1 Sept 1992
Bowser R, Müller H, Govindan B, Novick P
Abstract excerpt
The SEC8 and SEC15 genes are essential for exocytosis in the yeast Saccharomyces cerevisiae and exhibit strong genetic interactions with SEC4, a gene of the ras superfamily. The SEC8 gene encodes a hydrophilic protein of 122 kD, while the temperature-sensitive sec8-9 allele encodes a protein prem...
Topics
- Amino Acid Sequence
- Base Sequence
- Carrier Proteins
- Cell Membrane
- Cloning, Molecular
- Exocytosis
- Fungal Proteins
- GTP-Binding Proteins
- Genes, Fungal
- Molecular Sequence Data
- Molecular Weight
- Mutation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Solubility
- Vesicular Transport Proteins
- rab GTP-Binding Proteins