Article
Structural and functional dissection of a membrane glycoprotein required for vesicle budding from the endoplasmic reticulum.
Molecular and cellular biology - 1 Nov 1991
d'Enfert C, Barlowe C, Nishikawa S, Nakano A, Schekman R
Abstract excerpt
Sec12p is a membrane glycoprotein required for the formation of a vesicular intermediate in protein transport from the endoplasmic reticulum to the Golgi apparatus in Saccharomyces cerevisiae. Comparison of the N-linked glycosylation of Sec12p, a Sec12p-invertase hybrid protein, and a derivative of Sec12p lacking 71 carboxy-terminal amino acids showed that Sec12p is a type II membrane protein. Analysis of two...
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