Article
Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p.
The Journal of cell biology - 1 Oct 1995
Espenshade P, Gimeno R E, Holzmacher E, Teung P, Kaiser C A
Abstract excerpt
Temperature-sensitive mutations in the SEC16 gene of Saccharomyces cerevisiae block budding of transport vesicles from the ER. SEC16 was cloned by complementation of the sec16-1 mutation and encodes a 240-kD protein located in the insoluble, particulate component of cell lysates. Sec16p is released from this particulate fraction by high salt, but not by nonionic detergents or urea. Some Sec16p is localized to the...
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