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GWAS breakthroughs: mapping the journey from one locus to 393 significant coronary artery disease associations.

Cardiovascular research - 5 Nov 2024

Aherrahrou Rédouane, Reinberger Tobias, Hashmi Satwat, Erdmann Jeanette

Abstract excerpt

Coronary artery disease (CAD) poses a substantial threat to global health, leading to significant morbidity and mortality worldwide. It has a significant genetic component that has been studied through genome-wide association studies (GWAS) over the past 17 years. These studies have made progress with larger sample sizes, diverse ancestral backgrounds, and the discovery of multiple genomic regions related to CAD...

Topics

Humans
Genome-Wide Association Study
Coronary Artery Disease
Genetic Predisposition to Disease
Phenotype
Risk Assessment
Multifactorial Inheritance
Female
Genetic Loci
Prognosis
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sex Factors

Risk Factors

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 39073758
DOI: 10.1093/cvr/cvae161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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