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Pathogenesis of premature coronary artery disease: Focus on risk factors and genetic variants

9 Nov 2020

Abstract excerpt

The development of premature coronary artery disease (PCAD) is dependent on both genetic predisposition and traditional risk factors. Strategies for unraveling the genetic basis of PCAD have evolved with the advent of modern technologies. Genome-wide association studies (GWASs) have identified a considerable number of common genetic variants that are associated with PCAD. Most of these genetic variants are...

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PMID: 35224153
DOI: 10.1016/j.gendis.2020.11.003

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