Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between hemochromatosis genotype and lead exposure among elderly men: the normative aging study.

Environmental health perspectives - 1 May 2004

Wright Robert O, Silverman Edwin K, Schwartz Joel, Tsaih Shring-Wern, Senter Jody, Sparrow David, Weiss Scott T, Aro Antonio, Hu Howard

Abstract excerpt

Because body iron burden is inversely associated with lead absorption, genes associated with hemochromatosis may modify body lead burden. Our objective was to determine whether the C282Y and/or H63D hemochromatosis gene (HFE) is associated with body lead burden. Patella and tibia lead levels were measured by K X-ray fluorescence in subjects from the Normative Aging Study. DNA samples were genotyped for C282Y and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemochromatosis

Share to Linear Models

Share to Longitudinal Studies

Share to Multivariate Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 15121519
DOI: 10.1289/ehp.6581
PMCID: PMC1241970

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between hemochromatosis genotype and lead exposure among elderly men: the normative aging study.PMID 15121519Read ↗

Modifying effects of the HFE polymorphisms on the association between lead burden and cognitive decline.Semantic proximity Read ↗

Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.Semantic proximity Read ↗

The effect of the hemochromatosis (HFE) genotype on lead load and iron metabolism among lead smelter workers.Semantic proximity Read ↗

HFE H63D polymorphism as a modifier of the effect of cumulative lead exposure on pulse pressure: the Normative Aging Study.Semantic proximity Read ↗

Iron-processing genotypes, nutrient intakes, and cadmium levels in the Normative Aging Study: Evidence of sensitive subpopulations in cadmium risk assessment.Semantic proximity Read ↗

Modification of the association between lead exposure and amyotrophic lateral sclerosis by iron and oxidative stress related gene polymorphisms.Semantic proximity Read ↗

Haemochromatosis-associated HFE genotypes in English blood donors: age-related frequency and biochemical expression.Semantic proximity Read ↗

A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism.Semantic proximity Read ↗

HFE genotypes, haemochromatosis diagnosis and clinical outcomes at age 80 years: a prospective cohort study in the UK Biobank.Semantic proximity Read ↗

Effect of hemochromatosis genotype and lifestyle factors on iron and red cell indices in a community population.Semantic proximity Read ↗

Haemochromatosis Genotypes and Incident Dementia in a Prospective Study of Older Adults.Semantic proximity Read ↗

Influence of VDR and HFE polymorphisms on blood lead levels of occupationally exposed workers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.