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Article

Iron-processing genotypes, nutrient intakes, and cadmium levels in the Normative Aging Study: Evidence of sensitive subpopulations in cadmium risk assessment.

Environment international - 1 Oct 2018

Ciesielski Timothy H, Schwartz Joel, Bellinger David C, Hauser Russ, Amarasiriwardena Chitra, Sparrow David, Wright Robert O

Abstract excerpt

BACKGROUND: Because iron and cadmium share common transport mechanisms, iron-processing protein variants such as HFE C282Y, HFE H63D, and Transferrin P570S may influence cadmium metabolism. Our aim was to evaluate associations between common HFE and Transferrin polymorphisms and toenail cadmium levels among older men. METHODS: In a longitudinal cohort of men age 51-97, the Normative Aging Study (NAS), we...

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Source

Identifiers

PMID: 30059941
DOI: 10.1016/j.envint.2018.06.040

Genes

HFE

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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